My Ob gyn has recommended I up my dosage of Vitamin E to 1,000 I.U.  To alleviate the pain from the multiple cysts I get in my left breast when I am near menstruation.  Do you have studies that support this high dosage and/or the results that would indicate this to be effective? Your ob/gyn seems to know what she/he is doing in their suggestion to you -- you may wish to discuss your question directly with them. Our dosage recommendations on our website -- Recommended Dosage -- are suggestions from many of the doctors who use and suggest our products. We do not have direct studies available, but we have years of positive results reported by those who use our products. Also there are many reports available on the Internet. I would suggest going to GOOGLE and do a simple search like -- vitamin E and cysts – or -- vitamin E in menstruation.