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Vitamin E Meta-Analysis

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Council for Responsible Nutrition

EDITOR'S NOTE: The Council for Responsible Nutrition published a FACT SHEET -- Vitamin E meta-analysis in Annals of Internal Medicine: What’s wrong with this picture? --  in late 2004 to help consumers better understand the "negative" press about Vitamin E. This negative press continues to today -- and the information in the FACT SHEET is still tremendously valid for all to read! The FACT SHEET even discusses the "upcoming SELECT" test (which has just been published -- with negative press, of course) and prefaces that upcoming test as part of the meta-analysis process.

Please take the time to read this important FACT SHEET and, if you have any questions, feel free to call us at 800.833.4368, and we will be happy to discuss the positive truths about Vitamin E going back to the 1930s.

Below are excerpts from the topics discussed in the FACT SHEET:

FACT SHEET

Vitamin E meta-analysis in Annals of Internal Medicine: What’s wrong with this picture?

What is a meta-analysis?
A meta-analysis is not a clinical trial. It is a statistical technique for combining the results of many existing studies in order to clarify possible effects.

What is all-cause mortality?
A certain number of people in long term studies are going to die, and all-cause mortality is the number of people who died from any cause — whether or not the cause has anything to do with the purpose of the study.

What did this study find, overall?

Overall, Vitamin E supplementation did not  affect all-cause mortality.

What did the study find, relating to high and low doses of Vitamin E?
However, they go on to generalize, saying that people should avoid high-dose Vitamin E and indeed high doses of any Vitamin — a conclusion much more sweeping than is justified by their analysis.

Were there other findings?
The researchers also did a dose-response analysis of the clinical trials, which found a statistically significant (but very small) increase in mortality only when the Vitamin E dose was greater than 900 IU.  This is contrary to the finding in their main meta-analysis that doses over 400 IU might confer increased risk.

What were the 19 studies used in this meta-analysis?

Some of the studies involved over 20,000 people, and some involved only a few hundred people.  Doses used in the studies ranged from 16.5 IU to 2000 IU and were given for periods from one to 8 years . . . some of the studies found a benefit of Vitamin E for these purposes.

Do any of the studies show a benefit from Vitamin E?
Yes. Many of the 19 clinical studies used in this meta-analysis actually showed a health benefit from Vitamin E.

Do epidemiologic studies show a benefit from Vitamin E?
Yes. Numerous epidemiologic studies have shown a benefit from Vitamin E. 

Are more studies being done using high-dose Vitamin E?
Yes. A number of new clinical trials are now under way, and researchers are attempting to reassure the people enrolled in these trials that Vitamin E is safe and that the research should continue.

Was it reasonable to select 400 IU as the cutoff between low-dose and high-dose Vitamin E?

No. Four hundred IU was an arbitrary number.

How much Vitamin E is safe?
The Institute of Medicine, a scientific advisory body, has concluded that Vitamin E is safe for chronicuse in the general population at levels up to 1000 mg (1000 IU synthetic Vitamin E, 1500 IU natural Vitamin E).

What should people think about this meta-analysis?

Consumers who are already using Vitamin E should continue to use it with confidence, and people who are not currently using at least a multiVitamin containing Vitamin E should consider doing so, since the overwhelming majority of the population fails to get the recommended amount of Vitamin E from diet alone.

(Read report here)

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Television Commercial

AC Grace UNIQUE E Commercial

A.C. Grace Company produces NEW Television Commercial for UNIQUE E®!

A brand-new 30-second TV commercial will begin airing nationwide in the next few weeks! We wanted our customers and interested parties to get a Special Preview here on our website.

Click here or on the image at left to preview it!

SPECIAL NOTE: Our new national commercial has started airing on networks around the country. This campaign is designed to continue to 'get the word out' about UNIQUE E® -- the multi-E vitamin E that is UNIQUE, PURE & NATURAL.

 
UNIQUE E® Natural Moisturizer Wins Gold Medal Awards
FOR IMMEDIATE RELEASE

UNIQUE E® NATURAL MOISTURIZER receives Gold Medal Natural Beauty Products Awards!

Vitamin E specialist A.C. Grace Company’s new NATURAL Moisturizer voted top skin care product by two industry groups!

starburstgoldmedalBest of Natural Beauty AwardsBest of Expo Awards

Big Sandy, TX -- 22, March, 2010 – A.C. Grace Company today announced that its UNIQUE E® NATURAL MOISTURIZER product has been awarded top honors in the Skin Care Category from both Best of Natural Beauty Awards and Best of Expo 2010 Awards.

"Our Natural Moisturizer was four years in the making as we testing multiple formulas," says Lyn Capps, President of A.C. Grace. "In keeping with our mission to provide PURE, NATURAL products to the market, we wanted to make sure that all of the ingredients in this product were food grade, natural products that would benefit the skin health of our customers who have been using our UNIQUE E® line of vitamin E products for almost 50 years, and new customers who understand the benefits of Vitamin E in their diets and on their skin."

"The key base ingredient in UNIQUE E® NATURAL MOISTURIZER is 10% (by volume) of our PREMIER product, UNIQUE E® MIXED TOCOPHEROLS, which is a non-synthetic, natural form of High gamma-, High alpha-tocopherol concentrate including all four tocopherol isomers (alpha, beta, gamma and delta).  The unadulterated PURITY of the Vitamin E oil keeps the ingredients from separating like other cosmetic products that use lesser quality Vitamin E," Capps continued.  "It is our understanding that this product contains the highest amount of Vitamin E in any cosmetic product to date!"

The ingredients in UNIQUE E® NATURAL MOISTURIZER use a proprietary matrix-structure-formulation created specifically to bind the emollient ingredients with the antioxidant rich Vitamin E, and provide time-release 'hang-time' on the skin of up to seven hours. This matrix structure provides four key areas of natural benefit to the skin: 1) moisturizing; 2) absorption; 3) elasticity; and, 4) oxygenation.


Along with the recognized benefits to the skin from topical application of PURE Vitamin E products, clinical studies show powerful correlation to oral ingestion of Vitamin E along with application to the skin -- benefits from the 'inside-out' and the 'outside in!'

"We are thrilled to be recognized by our peers in the cosmeceuticals industry, just as we have been for decades in the dietary supplement industry," concluded Capps.  "We just want to make sure our core of dedicated, knowledgeable customers can continue knowing that A.C. Grace Company will always provide the 'best' products available!"

A.C. Grace Company was founded 1962 and is well-known as the Standard in the Vitamin E industry. They have been providing thousands of healthcare professionals in all fields of practice, their patients and tens of thousands of consumers worldwide, a line of PURE Multi-E products for nearly a half-century. The company also provides extensive education about the "Truth About Vitamin E by Application Based Science" through mailings and on their website.

Contact:     
Lyn Capps, President                            
A.C. Grace Company            
903.636.4368                            
www.acgrace.com

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A.C. Grace Sponsors Nutrition Workshop at ACAM
acam-spring

A.C. Grace Company sponsors Nutrition Workshop at ACAM Spring Event


Pre-conference workshop by Nutritionist David J. Getoff draws large attendance!

San Diego, CA -- April 22, 2010 – A.C. Grace Company provided an education grant to the American College for Advancement in Medicine in support of the day-long nutrition workshop presented by David J. Getoff and the Price-Pottenger Nutrition Foundation this past Wednesday, April 21st at the Sheraton San Diego.

David J. Getoff, CCN, CTN, FAAIM, who is Vice-President of the Price-Pottenger Nutrition Foundation, presented a workshop titled NUTRITION THAT HEALS From Generations of Research. Pioneering researchers in the field of health and nutrition have found a strong link between diet, vitality, and disease-free survival of all populations studied.  Today, those who continue to consume their traditional foods, which vary throughout the world, enjoy long-term health that is the envy of their “civilized” counterparts.  

In response to the need for reliable information on nutrition, ACAM and PPNF have partnered to offer a comprehensive program on diet and supplementation.  This seminar was the first part of an extensive educational program that will soon become available. This course is designed for all physicians, nutritionists, and other health care professionals who use nutrition in their practice, and for anyone interested in information they can trust.

Key topics covered in the seminar:
•    The importance of the pioneering research of Weston A. Price, DDS, and Francis M. Pottenger, Jr., MD.
•    How to apply the wisdom of traditional diets to prevent modern-day diseases and improve health.
•    What a healthy diet really is, how this has been validated, and what dietary changes are the most important while working with your patients.
•    The role of essential animal fats in human nutrition and the benefits of select vegetable fats when used properly.
•    Why kidney and liver laboratory tests are unreliable and the importance of supporting these organs with appropriate supplements.
•    The current misguided theory on cholesterol.
•    The myths surrounding vegetarianism.
•    Healthy and unhealthy dairy products.
•    Methods of reducing exposure to environmental toxins and effective ways to work on detoxifying your patient population.
•    Why we need nutritional supplements, with specific recommendations of products David finds to work best with his patients (no financial interest involved).
•    Recommended books and resources to use in educating your patients.  These include historical, multi-generational studies showing that veganism is not the best diet for long-term health.

In this workshop Getoff discussed at length that A.C. Grace Company's UNIQUE E® is the "only vitamin E worth taking."

During breaks, at lunch and in the following three days of the ACAM Spring Education Summit hundreds of health care professionals visited with representatives from A.C. Grace Company to understand why UNIQUE E® is UNIQUE, and how they can integrate it into protocols they use with their patients.

The Price-Pottenger Nutrition Foundation® is a non-profit, 501(c)(3) educational corporation, originally founded in 1952.  The foundation is committed to protecting, preserving, and disseminating the research of Drs. Price and Pottenger whose studies of the role of whole, living foods in human nutrition provide the basis for understanding our current state of health. PPNF publishes the quarterly Journal of Health and Healing and offers lectures, books, and audio/video materials on current health and nutrition issues.

David Getoff has a private practice in nutrition and traditional naturopathy in San Diego, CA and has been educating heath care professionals and the public on how to attain optimal health for the past 18 years.

 
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