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Alpha-Tocopherol a Detriment to Tocotrienol Benefits

Friday, 22 October 2010 00:00

Alpha-Tocopherol a Detriment to Tocotrienol Benefits (when taken together)

Japanese researchers have previously shown delta-tocotrienol to be the most potent anti-angiogenic Vitamin E compound._{(1, 2)}

In a recent study, published on pubmed.org, the same researchers tested the influence of tocopherol on the cytotoxic effects of delta-tocotrienol in human colorectal cancer cells. Tocopherol, and especially alpha-tocopherol was found to interfere with delta-tocotrienol's cytotoxic effects. Further, results indicate that alpha-tocopherol is not only less cytotic to cancer cells, but also reduces the anti-cancer effects of delta-tocotrienol by inhibiting its cellular uptake.₍₃₎

A.C. Grace Company's UNIQUE E® Tocotrienol is a naturally tocopherol-free DeltaGOLD® tocotrienol derived from the rain forest Annatto plant. Uniquely, UNIQUE E® Tocotrienol provides only the two most potent delta- and gamma-tocotrienol isomers, thus providing maximum tocotrienol benefit.

For information on the benefits provided by Annatto Tocotrienol, watch a recent segment by National Medical Report with Dr. Barrie Tan of American River Nutrition, the supplier of A.C. Grace Company's UNIQUE E® Tocotrienol.

The Tocotrienols Story

Read the PubMed abstract.

References:
1. Shibata, A, et al, delta-Tocotrienol suppresses VEGF induced angiogenesis whereas alpha-tocopherol does not. J Agric Food Chem, 2009. 57(18): p. 8696-704.
2. Shibata, A, et al, Tumor anti-angiogenic effect and mechanism of action of delta-tocotrienol. Biochem Pharmacol, 2008. 76(3): p. 330-9.
3. Shibata, A, et al, alpha-Tocopherol attenuates the cytotoxic effect of delta-tocotrienol in human colorectal adenocarcinoma cells. Biochem Biophys Res Commun.

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IMPORTANT NOTE: Since the launch of our UNIQUE E® Tocotrienol product in 2008, we have been educating doctors and their patients, health food stores, and consumers on the tremendous benefits of high-delta tocotrienol derived from the Annatto Plant in Brazil. This recent study validates what we have known from the beginning - that alpha-tocopherol inhibits the absorption of tocotrienols if taken together! This is great news for many who still have questions about what tocotrienols are and how they can help you in your diet.

Keep in mind that this does not mean that the tocopherol forms of the Vitamin E complex are not effective! A PURE, Natural Mixed Tocopherols Concentrate product HIGH in Gamma-Tocopherol and Alpha-Tocopherol, and including Delta- and Beta-Tocopherol is still recommended as a powerful anti-oxidant and major supporter of the cardiovascular and circulatory system.

With 93% of Americans being deficient in Vitamin E, it is very important to maintain a protocol using a GREAT Mixed Tocopherols with your morning meal and AnnattoTocotrienol with your evening meal.

Over 93% Of Americans Are Deficient In Vitamin E

Monday, 18 October 2010 00:00

IMPORTANT HEALTH ALERT!

Over 93% Of Americans Are Deficient In Vitamin E_1,2
(Your foods cannot provide what you need!)

For the price of a soft-drink or snack per day, you can supplement your diet with a PURE, NATURAL Vitamin E that will provide maximum benefits for managing your healthy lifestyle.

Doctor Tested: Application-Based Science^TM

For nearly a half-century, UNIQUE E^® VITAMIN E PRODUCTS have been the leading source of unadulterated, pure Vitamin E for doctors and their patients and consumers alike.

Vitamin E is well-recognized for providing many known health benefits:*

General Health

* Breast Cancer - studies show reduced risk

* Menopause & Hot Flashes - reduces negative effects

* Dermatological Health - promotes healthy skin

* Stretch Marks, Wounds & Scars - soothes and reduces

* Immune System - supports and promotes immune system

* Cancer - has shown malignant cell death in cancer cultures

* Inflammation - helps reduce pro-inflammatory molecules

* Eye Health - helps with cataracts and eye health

Cardiovascular & Circulatory Health

* Antioxidant - protects against the oxidation of important lipids

* Heart - supports overall cardiovascular and circulatory health

* Stroke - decreased carotid stenosis and reduced risk of stroke

* Blood Flow - enhances coronary blood flow

* Blood Pressure - decreases blood pressure

* Plaque - decreases plaque formation

* Cholesterol - assists in reducing cholesterol

* Diabetes - reduces triglyceride and diabetes risk

* Rouleaux - reduces and/or eliminates clumping of red blood cells

Aging and Immunity

* Alzheimer's Disease - has shown promising research in patients

* Memory - enhances focus and assists memory retention

* Oxidative Stress - decreases oxidative stress in older individuals

* Cell Level Health - helps maintain the integrity of cellular function

* Immune System - enhances immune function in the elderly

Already taking a Vitamin E?

Have you checked your label?

* Is it synthetic? (Tocopheryl acetate or succinate?)

* Does it contain fillers, colors, allergens and source oils?

* Does it contain mostly Alpha-Tocopherol?

A.C. Grace Company UNIQUE E^® Mixed Tocopherols Concentrate is the PUREST form of NATURAL MIXED TOCOPHEROLS with high Gamma- and high Alpha-Tocopherols along with Beta- and Delta- to provide these vitamin E compounds as found in nature - nuts, vegetable oils, leafy greens and whole grains.

UNIQUE E^® Tocotrienol (DeltaGOLD^®) from the Annatto plant provides the maximum benefits found in any Tocotrienol product with extremely high Delta-Tocotrienol and Gamma-Tocotrienol. Also, it DOES NOT contain ANY Tocopherols which have been found to inhibit absorption of Tocotrienols if taken together.

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"I use and recommend UNIQUE E® because I believe it to be absolutely the best Vitamin E complex product on the market." - David J. Getoff, CCN CTN

"I have consistently had better results since I switched to UNIQUE E®. I know it's the best." - Dr. Ron Schmid, N.D.

"I use UNIQUE E® because it is truly an all-natural Vitamin E with 300mg of gamma-tocopherol and 400 I.U. of alpha-tocopherol in each softgel." - Dr. Jerome L. Borochoff, M.D.

"I just wanted to tell you that UNIQUE E^® NATURAL MOISTURIZER is the BEST natural moisturizer on the market!" - Debbie C., Knoxville, TN

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Read more about how to start adding this vital nutrient BACK INTO YOUR DIET at these links: UNIQUE E^® Vitamin E Products and UNIQUE C.A.R.E.^TM Products (Complementary and Alternative Resources for Vitamin E).

1. Traber MG. How much vitamin E?. . . Just enough! Am J Clin Nutr. 2006 Nov;84(5):959-60.

2. Maras JE, Bermudez OI, Qiao N, Bakun PJ, Boody-Alter EL, Tucker KL. Intake of alpha-tocopherol is limited among US adults. J Am Diet Assoc. 2004 Apr;104(4):567-75.

*Statements in this article have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.

Vitamin E May Prevent Respiratory Infections in Elderly

Thursday, 12 August 2010 10:07

Vitamin E May Prevent Respiratory Infections in Elderly

BOSTON—Vitamin E supplementation may be a potential strategy to prevent respiratory tract infections (RIs) in the elderly. But the efficacy of vitamin E supplementation may depend on individual factors, including specific single nucleotide polymorphisms (SNPs) at immunoregulatory genes.

Researchers at Tufts University used data and DNA from a previous vitamin E intervention study—200 IU/d of vitamin E or a placebo for one year—in elderly nursing home residents to examine vitamin E-gene interactions for incidence of RI (Am J Clin Nutr. 2010;92: 106-114).

The effect of vitamin E on lower RI depended on sex and the SNP at IL-10 –819GA. Subjects with the least prevalent genotypes at IL-2 –330AC, IL-10 –819GA and IL-10 –1082CT had a lower incidence of RI independent of vitamin E supplementation.

The researchers concluded: “Studies that evaluate the effect of vitamin E on RIs should consider both genetic factors and sex because our results suggest that both may have a significant bearing on the efficacy of vitamin E. Furthermore, common SNPs at cytokine genes may contribute to the individual risk of RIs in the elderly."

See original article here

NPA Calls Consumer Reports Article 'An Attack on Supplements'

Wednesday, 04 August 2010 09:50

NPA Calls Consumer Reports Article 'An Attack on Supplements'
States that the story’s data are questionable

The Natural Products Association has issued the following statement concerning the September 2010 issue of Consumer Reports magazine:

The latest edition of Consumer Reports is an attack on dietary supplements -- including a call for additional regulation of the industry -- that presents a far from balanced and accurate representation of the industry or the laws that regulate it.
For example, a number of the mentioned products are actually illegal drugs – not supplements, and only available from those violating the laws. (See: FDA: Dietary Supplement Alerts and Safety Information)
The NPA questions the data Consumer Reports is using to suggest the dietary supplement industry suffers from inadequate quality controls. In actuality, evidence from the government suggests the contrary. Earlier this year, the U.S.

Government Accountability Office (GAO) tested a number of products finding only trace amounts of contaminants, leading the FDA to testify before Congress that “we do not believe these levels represent a significant risk to health.” It is curious that Consumers Union, publisher of Consumer Reports and also a witness at that hearing, did not mention this testimony in the article.

The U.S. supplement industry has an enviable safety record, especially when compared with other FDA-regulated sectors, and the industry has supported and continues to support measures to make supplements even safer.
- NPA supported enactment of the Dietary Supplement Health and Education Act (DSHEA).
- NPA supported enactment of the legislation creating the Adverse Event Reporting system.
- NPA supported implementation by the Food and Drug Administration of Good Manufacturing Practices, even launching our own GMP certification program in 1999.
NPA supports the full implementation of DSHEA - including providing additional resources for these agencies. To that end, NPA endorses S. 3414, the Dietary Supplement Full Implementation and Enforcement Act of 2010, introduced by Sen. Tom Harkin (D-IA) and Sen. Orrin Hatch (R-UT).

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About the Natural Products Association
Founded in 1936, the Natural Products Association is the nation's largest and oldest non-profit organization dedicated to the natural products industry. The Natural Products Association represents more than 10,000 retailers, manufacturers, wholesalers and distributors of natural products, including foods, dietary supplements, and health/beauty aids.
www.NPAinfo.org

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