UNIQUE E® Mixed Tocopherols Concentrate – 120 Softgels
UNIQUE E® Mixed Tocopherols Concentrate (OPTIMUM E COMPLEX)
Mixed Tocopherols – THE STANDARD IN THE INDUSTRY for 50 years! PURE, natural UNIQUE E® Vitamin E concentrate consists of the natural form of Vitamin E containing NO fillers, allergens, colors, or vegetable oil. Kosher friendly. Each 700mg beef softgel mixed tocopherols contains the highest concentration of the complete Vitamin E tocopherol complex — HIGH-Gamma, HIGH-Alpha, with Beta and Delta isomers — completely void of fillers or additives that can turn rancid. This all-natural, PURE Vitamin E concentrate consists of the natural form of Vitamin E as obtained through the diet and as used by the body.
Mixed Tocopherols – Available in two sizes — 120-softgel bottle and an “easy travel size” 30-softgel bottle.
- Contains the Highest Concentrations of PURE Vitamin E available
- 700mg of the natural vitamin E complex of molecules
- High d-gamma tocopherol, with a minimum of 300mg per softgel
- 400 I.U. of alpha-tocopherol (268mg) per softgel
- Strict quality control measures that conform to our high standards
Does Not Contain
- Void of Fillers, Allergens, or Additives
- Contains no soy oil, soy protein, gluten, or other fillers
- Kosher friendly
Vitamin E has been found to provide many valuable Health Benefits:
- Supports overall cardiovascular and circulatory health*
- Promotes healthy coronary blood flow*
- Provides antioxidant support*
- Supports the body’s ability to appropriately process and utilize important lipids*
- Helps in the maintenance of cholesterol levels that are already within the normal range.*
- Helps support healthy red blood cell flow*
- Supports healthy focus and memory retention*
- Helps to promote healthy brain function*
- Provides antioxidant support throughout the body *
- Helps maintain the integrity of cellular function*
- Supports healthy immune function*
- Promotes eye health*
- Supports and promotes the immune system*
- Supports the body’s ability to regulate pro-inflammatory molecules, including C-reactive protein*
- May be applied externally as a topical to promote dermal health (see also our UNIQUE E® Mixed Tocopherols Concentrate Oil)*
The Science Behind the UNIQUE E® Product
Vitamin E is a complex of eight molecules that work together synergistically. Taking a Vitamin E supplement with only d-alpha tocopherol instead of the entire mixed tocopherols family of isomers can actually deplete the level of d-gamma tocopherol in the body.
The mainstream medical community only recently recognized the importance of d-gamma tocopherol. But A.C. Grace has noted the importance of d-gamma tocopherol since 1962. Our proprietary formula of concentrated tocopherols is specifically designed to provide the highest biological activity and maximum synergistic benefits of the all-natural complex.
Campbell SE, Stone WL, Whaley SG, Qui M, Krishnan K; gamma-tocopherol up-regulates peroxisome proliferator activated receptor (PPAR) gamma expression in SW 480 human colon cancer cell lines.
Handelman GJ, Machlin LJ, Fitch K, Weiter JJ, Dratz EA; oral alpha-tocopherol supplements decrease plasma gamma-tocopherol levels in humans. Journal of Nutrition 1985 Jun;115(6):807-13.
Jiang Q, Wong J, Fyrst H, Saba JD, Ames BN; gamma-tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis — Jiang Q, Wong J, Ames BN; [gamma]-tocopherol induces apoptosis in androgen-responsive LNCaP Prostate Cancer Cells via Caspase-Dependent and Independent Mechanisms.
Jiang Q, Ames BH; gamma-tocopherol but not alpha-tocopherol, decreases pro-inflammatory eicosanoids and inflammation damage in rats. — Jiang Q, Elson-Schwab I, Courtemanche C, Ames BN; gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells.
There are three general dosage recommendations:
Maintenance Dose: 1-3 softgels daily
Therapeutic Dose: 1 softgel (400 I.U.) per 40 pounds of body weight
Intensive Dose: 4-6 softgel regardless of body weight
General Dosage Rules:
Maximum dose 6 softgel (2400 I.U.)—more than this is usually wasted.
Entire dosage to be taken ALL AT ONCE.
Best effect when dosage is taken WITH a meal.
What about vitamin E and drug interactions?
People using drugs such as blood-thinners, cholesterol medications, blood pressure medications, etc, should always start with 1 softgel (400 I.U.) and work up to optimum dosage over time as needed. Vitamin E can temporarily increase blood pressure in individuals with high blood pressure—monitoring dosage is required. However, it has been reported that, over time, vitamin E supplementation can support healthy blood pressure levels. Always speak with your primary health care provider before adding this or any other dietary supplement to your daily health regimen.* Vitamin E is fat soluble, what about liver toxicity, what level is safe?
Unlike other fat soluble vitamins, vitamin E is NOT accumulated in the liver. This astonishing fact was recently proven in a paper entitled, Vitamin E Trafficking (see references below). The authors report, “the liver does not accumulate ‘toxic’ amounts of vitamin E. Excess vitamin E is not accumulated in the liver, but is excreted, mostly in bile, via a p-glycoprotein (ABCB4)-mediated process.” Speak with your primary health care provider to determine a dosage that is appropriate for your health goals.*
Ann. N.Y. Acad. Sci. 1031: 1–’D012 (2004). doi: 10.1196/annals.1331.001 Vitamin E Trafficking Maret G. Trabera, Graham W. Burtonb and Robert L. HamiltoncaLinus Pauling Institute, Oregon State University, Corvallis, Oregon 97331, USA; bOccell, Inc., Ottawa, Ontario K1B 5B0, Canada; cDepartment of Anatomy, Cardiovascular Research Institute, University of California, San Francisco, California 94143, USA
Kappus H, Diplock AT. Tolerance and safety of vitamin E: a toxicological position report. Free Radic Biol Med 1992;13:55–’D074.
Vitamins E and C are safe across a broad range of intakes. Hathcock JN, Azzi A, Blumberg J, Bray T, Dickinson A, Frei B, Jialal I, Johnston CS, Kelly FJ, Kraemer K, Packer L, Parthasarathy S, Sies H, Traber MG. Am J Clin Nutr. 2005 Apr;81(4):736-45.