Cardio Unique E® – 60 Capsules in a Capsule
$42.35
- Unique Cardio E Works Two Different Ways – Most supplements only do one thing. Cardio Unique E actually lowers cholesterol in two ways at the same time — it signals your liver to pull cholesterol out of your blood, and it grabs onto cholesterol in your gut so your body can flush it out. Two jobs, one capsule.
- Real Studies. Real Results. This isn’t just marketing — Cardio E has been tested in five separate clinical trials. On average, people saw their bad (LDL) cholesterol drop by 15% and their triglycerides drop by 10–15%. No diet changes. No new medications. Just the probiotic doing its job.
- Safe to Take Even If You’re Already on Cholesterol Medication – Already taking a statin like Lipitor or Crestor? No problem. A clinical study confirmed that Cardio Unique E is safe to take alongside statins. Plus, the added Vitamin E helps protect your arteries from damage — something statins don’t do on their own.
- Cardio E is Built to Actually Work – Live probiotics are fragile. That’s why this formula uses a special capsule-inside-a-capsule design to keep the probiotic alive and separated from the Vitamin E oil until it reaches your gut. It’s also FDA-recognized as safe (GRAS status) — so you know exactly what you’re getting.
*Statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Support your heart from the inside out – every single day.
Cardio Unique E combines a patented probiotic blend with a meaningful does of antioxidant vitamin E to help maintain cholesterol levels protect against LDL oxidation, and promote cardiovascular wellness through the gut-liver axis. Each two-capsule serving delivers a 1:1:1 ratio of three clinically studied strains of Lactiplantibacillus plantarum (CECT 7527, 7528, 7529), shown to support healthy lipid metabolism and vascular function. Now it also includes 100 IU of Natural Alpha tocopherol (Vitamin E), plus delta-and gamma-tocopherol isomers for broad-spectrum antioxidant support.
Unique E® provides the optimum ratio of tocopherols to deliver the maximum health benefits. *
A capsule in a capsule:
- Inner capsule contains KABP Metabalance — a once-a-day probiotic combination of three Lactobacillus plantarum strains
- Outer capsule contains UNIQUE E® Vitamin E Tocopherol complex — d-alpha, d-gamma, and d-delta tocopherols
UNIQUE E® Tocopherols are encapsulated in Kosher beef softgels and consist of the natural form of vitamin E without containing fillers, allergens, colors, or vegetable oil. The concentrated formula provides the synergistic benefits of the complete vitamin E tocopherol complex (d-alpha, d-beta, d-gamma, and d-delta tocopherols) and delivers the highest biological activity by providing the optimum proportions of the complex in the body. The natural formulation includes a lower concentration (12%) of d-alpha and a higher concentration (~60%) of d-gamma tocopherols in UNIQUE E® vitamin E aimed to increase absorption of vitamin E by the body, requiring fewer number of softgels daily. UNIQUE E® softgel has a mild taste and is easy to swallow.
KABP Metabalance is a patented, clinically tested, once-a-day probiotic combination of three Lactobacillus plantarum strains. These strains showed:
- a highly superior ability to survive in the acidic environment of the stomach and intestines
- an ability to adhere to intestinal cells that was four times higher than the other common strains
KABP Metabalance clinical trials have shown a benefit to cholesterol metabolism via 3 mechanisms of action associated with healthy cholesterol levels:
- Disrupting the action of bile acids by bile salt hydrolase (BSH) production, thus preventing the emulsification and absorption of dietary cholesterol
- Direct binding of dietary cholesterol, interfering with its absorption into the blood
- Inhibit the body’s own production of cholesterol in the liver KABP Metabalance strains were shown to produce an enzyme called BSH. BSH cleaves bile acids, hindering their function. Dietary cholesterol can’t enter the bloodstream from the intestine without the aid of bile and lipoprotein carriers.
Cardiovascular Health
- Supports overall cardiovascular and circulatory health*
- Promotes healthy coronary blood flow*
- Provides antioxidant support and reduces inflammation*
- Supports the body’s ability to appropriately process and utilize important lipids*
- Helps maintain healthy cholesterol levels*
- Helps support healthy red blood cell flow*
- Helps reduce the risk of cardiovascular disease by slowing plaque buildup in arteries*
- Can be safely combined with statins, antihypertensive and antidiabetic medication*
General Health
- Aids individuals with dry or rough skin, muscle weakness, vision problems, weakened immune system, and nerve damage*
- Balance gut microflora for systemic wellness*
Aging
- Associated with reduced cognitive decline in older adults*
- Supports healthy immune function*
See and Taste the Difference!
Most vitamin E on the market looks light in color – that’s because it may contain up to 50% vegetable oil as a filler which can turn rancid and have a bad taste.
Cardio UNIQUE E® recommended dose is 2 capsules daily:
- 100 IU Vitamin E – alpha, beta, delta, gamma tocopherol complex
- 1.2 billion CFUs (3 Lactobacillus plantarum strains)
Ingredients:
KABP® Cardio Probiotic
- Lactiplantibacillus plantarum KABP®-011
- Lactiplantibacillus plantarum KABP®-012
- Lactiplantibacillus plantarum KABP®-013
Vitamin E (100 IU Natural Alpha Tocopherol)
High Gamma Tocopherol Blend (d-gamma tocopherol, d-delta tocopherol)
Other Ingredients: Microcrystalline cellulose

FAQs
The shelf life of nutritional supplements is indicated near the UPC code on the label. There is normally a date stamp that shows the month and year of “recommended” expiry. We use a 2 or 3-year time stamp by regulation. However, UNIQUE E® Mixed Tocopherols are pure, have no fillers, diluents, vegetable oil, or other additives that may turn the product rancid. What turns vitamin E rancid (causing it to oxidize and potentially expire) is the additional oils contained along with the vitamin E. As mentioned before, we do not have any extra oils – it is pure vitamin E oil that does not turn rancid. One of the best ways to check your softgels is to bite into one – it should have a mild bland taste.
- Mixed Tocopherols – the source for the Vitamin E in this product is a combination of rape seeds, sunflower and soybean oil. However, A.C. Grace uses a proprietary distillation process that extracts all soy oil out of the Vitamin E oil, thus providing a pure, natural form. So, inside the softgel or pump bottle is a pure, natural concentrate mix of alpha, beta, gamma and delta tocopherols with no fillers, additives, colors, wheat, gluten, soy oil, soy protein or flax. Our softgels are a beef gelatin. Our product is certified to be PCR-negative which is the industry recognized classification for products that have been produced and distilled to remove any and all contaminates that could affect purity.
- Tocotrienols – the source for the Vitamin E in this product is the Annatto Bean. The same processes are used to provide a pure Tocotrienol product with NO fillers, additives, colors, wheat, gluten, soy oil, soy protein or flax. Our softgels are a beef gelatin.
Yes! UNIQUE E® MIXED TOCOPHEROLS CONCENTRATE is un-esterified, pure, natural and high in gamma- and alpha-tocopherol, with proprietary amounts of beta- and delta-tocopherol. It is the full complex of tocopherols as obtained through diet and used by the body. Because it is pure (with NO allergens, fillers, colors, wheat, gluten, soy oil, soy protein or flax) it provides maximum Vitamin E benefit to the body.
Although our product is derived from soybeans, it does not contain any soy DNA protein because they are destroyed during distillation. Our product is certified to be PCR-negative which is the industry recognized classification for products that have been produced and distilled to remove any and all contaminates that could affect purity. Scientists state that there is no difference between a GMO and non-GMO product that is PCR-negative.
Our capsules are a beef gelatin. Certified to be free of any concern about “mad cow” issues. As listed on out label, the softgels themselves are made of beef gelatin, glycerin, and water
This question should be discussed with your primary health care professional. If you do not have a doctor or nutritionist to discuss this with, we may be able to direct you to one of our trusted partners that understand how vitamin E interacts with various medications and existing health conditions.
Science
When BSH is deconjugated, it cannot emulsify cholesterol for intestinal absorption into the blood.
Without bile emulsification, the undigested cholesterol passes through the digestive tract in the feces, effectively removing it from the body. KABP Metabalance strains have also been shown to directly bind to cholesterol molecules, which can keep it from being absorbed into the bloodstream (Bosch et al. 2014).
Like many probiotic bacteria, Lactobacillus plantarum strains produce short-chain fatty acids (SCFA) from dietary fibers. SCFAs inhibit the body’s own production of cholesterol by decreasing the expression of enzymes required for cholesterol synthesis in the liver (den Besten et al. 2013). They can also decrease the redistribution of cholesterol from the blood to the liver (Dora et al. 2002). This action of SCFAs inhibits the body’s production of cholesterol.
References
In clinical trials, participants taking the KABP® Cardio probiotic blend saw a reduction in total cholesterol (TC), LDL (~20%), LDL to HDL ratio, and triglyceride (TG) (~15%) levels—all without altering their diet or medication. HDL levels were not reduced.
Clinical trials conducted with multiple populations including:
- statin users
- overweight adults (BMI: 25.0-29.9 kg/m2)
- healthy Caucasian adults with:
- TC ≥200 mg/dL;
- LDL-C ≥160 mg/dL;
- TC 200-300 mg/dL and
LDL-C 130-190 mg/dL
- Asian adults with LDL-C between 130-200 mg/dL and TG 110-550 mg/dL












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